S04-01 Calfacilitin: A new player in neural induction

S04-01 Calfacilitin: A new player in neural induction Costis Papanayotou, Ping Liao, Song-Quing Lu, Lei Zhu, Alex Shaw, Andrea Streit, Dejie Yu, Tuck Wah Soong, Claudio D. Stern, Guojun Sheng University College London, London, United Kingdom National University of Singapore, Singapore, Singapore National Neuroscience Institute, Singapore, Singapore King’s College London, London, United Kingdom ...

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S04-02 How many ways to make a chordate: Comparison of the developmental programmes of ascidians and vertebrates

S04-01 Calfacilitin: A new player in neural induction Costis Papanayotou, Ping Liao, Song-Quing Lu, Lei Zhu, Alex Shaw, Andrea Streit, Dejie Yu, Tuck Wah Soong, Claudio D. Stern, Guojun Sheng University College London, London, United Kingdom National University of Singapore, Singapore, Singapore National Neuroscience Institute, Singapore, Singapore King’s College London, London, United Kingdom ...

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S04-03 Dynamic patterning of the vertebrate neural tube

S04-01 Calfacilitin: A new player in neural induction Costis Papanayotou, Ping Liao, Song-Quing Lu, Lei Zhu, Alex Shaw, Andrea Streit, Dejie Yu, Tuck Wah Soong, Claudio D. Stern, Guojun Sheng University College London, London, United Kingdom National University of Singapore, Singapore, Singapore National Neuroscience Institute, Singapore, Singapore King’s College London, London, United Kingdom ...

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Calfacilitin is a calcium channel modulator essential for initiation of neural plate development

Calcium fluxes have been implicated in the specification of the vertebrate embryonic nervous system for some time, but how these fluxes are regulated and how they relate to the rest of the neural induction cascade is unknown. Here we describe Calfacilitin, a transmembrane calcium channel facilitator that increases calcium flux by generating a larger window current and slowing inactivation of th...

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A new player in Pol II pausing.

Transcriptional control plays a primary role in gene expression and can be exerted at multiple levels of the transcription process, such as RNA polymerase recruitment and promoter-proximal pausing. A recent report published in The EMBO Journal (Li and Gilmour, 2013) provides new insights into the regulation of a large class of paused genes through the identification of a novel transcription fac...

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S04-01 Calfacilitin: A new player in neural induction

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